How to Treat & Diagnose Hyperpyrexia 41.5ºC
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How to Treat & Diagnose Hyperpyrexia 41.5ºC

If anybody feels a high body temperature, then no worries – the doctors are available to treat you with more care. But you cannot say that this temperature-raising condition is hyperpyrexia because you never know the causes. On the other hand, the term hyper-pyrexia is another term for very high fever. A person with this medical condition who has a body temperature of more than 106.7ºF or 41.5ºC is considered hyper-pyrexia.

Hyper-pyrexia is an emergency that requires immediate medical attention from professionals. The doctors take care of this tired condition because it creates tiredness in your body. This conditional fever is never an illness in itself. Instead, they are symptoms of other issues like viral or bacterial infections that cause most fevers. To know more about it, you have to read the blog and let us know if this blog is informative for you or not

What Is Hyperpyrexia – High Fever

Hyper-pyrexia is a temperature-raising condition where the body temperature goes above 106.7ºF or 41.5ºC due to changes in the hypothalamus. The hypothalamus is the organ of the brain that regulates the temperature of your body. In this condition, the body temperature changes during the day and varies throughout your lifetime. This condition is known as high fever (hyper-pyrexia).

Hyper-pyrexia is a life-threatening emergency that requires urgent medical care, and without providing proper treatment, hyper-pyrexia can lead to cause long-term complications or death. On the other hand, sometimes your body temperature also increases because of some external factors such as high ambient temperature then this condition does not belong to hyper-pyrexia.

Causes of Hyper-pyrexia

Hyperpyrexia is a kind of high fever that does not cause something severe. When it happens, it causes various symptoms, but before explaining symptoms – we will go through the causes and let’s discuss them.

malignant hyperpyrexia
malignant hyperpyrexia
  • Infections

Many infections, such as bacterial, parasitic, or viral infections, cause hyper-pyrexia. Another common hype fever that you will know is malaria, which is caused by protozoa, a most infectious cause of hyper-pyrexia.

These are the infections that cause hyper-pyrexia, and it includes:

  1. Streptococcus pneumonia, S. aureus & H. influenza bacterial infection.
  2. enterovirus & influenza A viral infections
  3. Malarial infection – Malaria

Sepsis is a life-threatening complication which is also known as hyperpyrexia. And causes an infection in humans. In sepsis, your body releases various compounds into your bloodstream that help fight infections. This can also produce a severe inflammatory response that may lead to organ dysfunction or failure.

  • Anesthesia

When a person comes with exposure to some anesthetic drugs, then it can cause extremely high body temperature. This is also known as malignant hyperthermia. It is associated with a quick increase in body temperature, metabolic acidosis, and generalized muscular rigidity, and this condition leads to fatal for people.

  • Heat Stroke

During summer, heatstroke is the most common condition with almost every person. It includes older adults, young children, individuals with chronic illnesses. Heatstroke is when your body temperature increases and goes on to a dangerous level. This can also be caused by overexerting yourself in hot weather. To overcome the heatstroke attack, you should drink more water to hydrate yourself and stay away from a stroke.

  • Thyroid Storm

A thyroid storm is a rare condition where the body produces thyroid hormone in a more quantity. And this excess hormone production can disrupt the body’s temperature regulation, which is why it can cause hyperpyrexia. For the treatment purpose, you can consult with your doctor, and your doctor will see your previous reports, symptoms, and lab tests to confirm thyroid storm.

What Are the Hyper-pyrexia Symptoms? 

These are symptoms of hyper-pyrexia which vary from person to person. And it depends on how long the condition lasts and worsens. Here are the following symptoms include:

parkinsonism hyperpyrexia syndrome
parkinsonism hyperpyrexia syndrome
  • Increased thirst for water
  • Dizziness & Muscles Cramps
  • Nausea & light-headedness
  • Fatigue & weakness
  • Extreme sweating

As the temperature increases, it can also cause more severe symptoms, and the severity of symptoms can increase more. This condition cause multiple symptoms are:

  • Headache & contracted pupils
  • Mild confusion or vomiting
  • Cool skin, pale & upset stomach
  • Inability to urinate

We can say it is considered a medical emergency, and if it is left untreated, organ dysfunction and death can occur. So, consult your doctor in that condition immediately.

How to Diagnose Hyperpyrexia

Diagnosing hyper-pyrexia is not complicated because it can diagnose quickly by using a thermometer. When the thermometer told you reading around 106.7ºF or 41.5ºC or above indicates hyper-pyrexia. Hyper-pyrexia always has an underlying cause, and pinpointing that cause can sometimes be challenging.

If you know that you have hyper-pyrexia, then you must look for medical care as soon as possible. For analyzing and cause of the hyper-pyrexia, the doctor will study your medical and travel history; then, he will check your physical condition and run several tests. These are the test which includes:

  • Blood Tests are used to check the sign of infection.
  • Thyroid function tests are used to check thyroid storms.
  • Imaging studies are used to check intracranial hemorrhage.

Depending on your previous medical history and your current condition, your doctor will suggest further testing.

How to Treat Hyperpyrexia

Hyper-pyrexia must not progress as an emergency requiring immediate medical attention to prevent organ damage and death. In the meantime, you can take the following steps to relieve the fever:

what is hyperpyrexia
what is hyperpyrexia
  • Sponge your skin with cold water or remove any extra clothing
  • Taking nonsteroidal anti-inflammatory medications on time is important. Please do not give aspirin to 19 years children or below age.
  • Hydration via IV or drinking liquids.

Based on the underlying cause of hyperpyrexia, your doctor will decide what treatment you need. For instance, if there is an infection, then your doctor will treat the infection. In the case of anesthesia-induced fever, your doctor will stop the anesthesia and give you medication to control it. Similarly, if you experience hyper-pyrexia while taking a drug, you should discontinue it and look for supportive care immediately. By seeing these conditions, the doctor will suggest NSAIDs & corticosteroids, which are used to treat hyper-pyrexia, which is also caused by intracranial hemorrhage.

COVID-19 Leads to Hyperpyrexia – Pandemic

Hypothermia is a condition in which a person’s body temperature rises as a result of an abnormal increase in the hypothalamic-thermoregulatory set. It is normal for everyone to experience fever during COVID-19. However, the outbreak has become a global health emergency. And the condition with COVID-19 has not been studied yet. However, clinical outcomes are revealed in COVID-19 during the hospitalization of Corona patients. It has been reported that patients have died suddenly as a result of their body temperature rising, and they could not withstand it. This mechanism of hyper-pyrexia is still mysterious, and future studies are underway to understand it better.


In conclusion, hyperpyrexia is a rising body temperature that requires the immediate medical facility to get back away from this annoying condition. Everyone should know about this pandemic, like the symptoms, causes, treatment, and diagnosis during this pandemic era. In this article, you will learn about these mentioned above terms, and you should tell the other person for the consultancy or to provide awareness in our society.

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